Biological specimen 3D morphology and refractive index separation

Biological specimen 3D morphology and refractive index separation

Real-time non-invasive quantitative measurement and analysis of the 3D morphology and the refractive index of cells, unicellular organisms or more complex biological specimens is of great importance in visualising and studying biological processes in living specimens. The measurements obtained can be used to assess and quantify cellular swelling resulting from physiological/pathological processes, or external stimulation - for example drug screening.